In Major League Baseball, betting on the run line is a type of spread betting designed for a lower-scoring sport. The run line typically sets a fixed spread of 1.5 runs between the favorite and the underdog. In today’s post, your friends at MyTopSportsbooks are here to help you understand how to approach run line bets with a solid strategy. To win a run line bet on the favorite, that team must win by two or more runs. If you’re betting on the underdog, they can either win the game outright or lose by just one run for your bet to cash.

Similarities between Moneyline and MLB Run Line

Run line betting is similar to moneyline betting in that you’re still picking a team to win. However, the run line in MLB is more like a point spread, similar to what you see in NFL betting — the most popular format in football wagering. In baseball, the standard run line is set at 1.5 runs, with favorites listed at -1.5 and underdogs at +1.5. This line rarely changes, but there are exceptions. Some sportsbooks offer alternate run lines at 2.5 or even 3.5 runs, with adjusted odds to reflect the added risk or advantage.

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A Baseball Run Line Example

New York Yankees, -1.5, -120 @ Toronto Blue Jays, +1.5, +150

In this hypothetical example, the Yankees would be the favorites at -1.5. To win a bet on New York, they’d need to beat the Blue Jays by two or more runs. On the other hand, if you bet on the underdog Blue Jays at +1.5, your bet wins as long as Toronto either wins the game outright or loses by exactly one run — since the spread gives them a 1.5-run advantage.

Baseball Run Line Betting Strategy

Baseball Run Line Betting Strategy

Run-line betting on MLB games isn’t as easy as it looks. Many sports bettors often default to betting on the favorite because they think they know that the favorite will win by two or more runs. Not to mention, there is a more significant payout based on higher odds of the favorite winning by more than two runs.

In the 2024 MLB season, 28% of games were settled by a one-run margin. This is much higher than you might expect. The high frequency of one-run games makes it difficult to determine which team will cover on the run line and which team won’t cover.

What the squares – casual bettors – don’t account for is the disadvantage a home-team favorite faces. The home team favorite must win by two runs, which isn’t an automatic result just because they are the favorite. In baseball, if the home team is ahead in the bottom of the ninth inning, they don’t take their last at-bat, as the game is won based on the completion of the number of innings played. This leads to many one-run victories, and the favorites often lose because of the quirk in the rules. The home team gets one less at-bat to build a winning score that is a single run when all is said and done.

To avoid unnecessary losses, a sports bettor is wise to stay away from the home team favorite and laying 1.5 runs. For a long-term strategy to provide consistent profits, bet like the sharps and take the underdog and the +1.5 on the run line. Sometimes you can get even money on the run line to place a value bet that turns into profit.

Moneyline vs the Run Line

In short, the run line is a baseball’s version of point spread betting where one team gets 1.5 runs while the other team spots the underdog 1.5 runs. The other common MLB bet is on the Moneyline for baseball games; let’s look at the differences between the two bets for baseball. The NHL has a version of the run line, and it is called the puck line and works the same way run line odds do. You can get promos from online sportsbooks like BetMGM, and Draftkings for a matchup on MLB or NBA games.

What is a Moneyline Bet on Baseball?

What is a Moneyline Bet on Baseball?

A Moneyline bet on MLB games is the easiest bet you can make. The hard part is picking a winner, and you have a 50-50 chance of doing so. On the Moneyline odds, at betting sites or apps, runs don’t matter; what does is the final score after nine innings or 8.5 innings if the home team is leading.

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The MLB odds are indicated by plus or minus signs, with plus signs indicating underdogs and minus signs indicating more favored team. As of July 2025, the Dodgers have odds of +175 for NLCS.

In another hypothetical example for the Moneyline, imagine the Toronto Blue Jays were +120, and the New York Yankees were -160. To win $100 betting on the Yankees, you must wager $160. If you win, you get your original bet of $160 plus the $100 for a total of $260. If you lose, you are out the initial bet of $160. If you take the underdog Blue Jays at +120 and win, you receive $120 plus the $100, and you’re up $220. The underdog bet is a risk, no doubt about it, but under the right circumstances, value can be evident.

What are Alternate Run Lines?

If you don’t like what the run line is serving up and you want better odds, most sportsbooks have alternate lines for sports bettors who want more say in the betting odds, and the odds will shift accordingly. It works a little like a teaser bet; you tease the run line up as high as you feel comfortable.

With a higher risk – giving up more runs – come higher rewards in the form of bigger payouts on wins. Oddsmakers will price your risk according to what the margin of victory will be based on handicapping alternative run lines.  If you choose to take Colorado Rockies over the Washington Nationals at -3.5, that sports bet is yours to make.

Frank Lorenzo
Frank Lorenzo
MTS Co-Founder
Geoff Johnson
Geoff Johnson
MTS Co-Founder